Clinical Research Department

At West Orange Endocrinology, we lead the way in endocrine and cardiometabolic research, bringing the latest treatments to our patients in Central Florida. Our goal is simple: improve care, enhance outcomes, and drive innovation. Dr. Jose M. Mandry, who has served the Orlando area since 1989, has been a research leader since the early 1990s and has been the Principal Investigator for numerous clinical studies since 2010.

Mission and Vision Statement

We Care

WOE Research was founded to advance medical care for patients managing chronic diseases. Our clinical trials provide participants access to cutting-edge treatments and education about their condition—at no cost. All products and testing are provided by the sponsor, enabling patients to benefit from the latest investigational medications and devices while contributing to medical research.

Clinical Care & Safety

Before any new therapy or device can be sold, it must pass rigorous FDA-approved testing phases. At WOE Research, we focus exclusively on trials that have completed all safety phases, ensuring minimal risk to participants. Our studies compare new treatments to established standards, helping demonstrate effectiveness while prioritizing patient safety.

Our Clinical Research Team

Dr. Jose Mandry M.D.

Principal Investigator

Maria Freire, PA-C

Sub - Investigator

Dr. Oscarina Herrera, M.D.

Sub - Investigator

Mary Mandry, MS, RD, LD/N

Site Administrator

Dr. Maria Marulanda, M.D.

Sub-Investigator and Site Director

Dr. Ineska Freire, M.D.

Senior Clinical Research Coordinator

Jhon Freire BSB

Operations Manager & Regularory

Dr. Eliana Caiafa, M.D.

Clinical Research Coordinator

Dr. Marielena Roedan, M.D.

Clinical Research Coordinator Assistant

Sponsors and CRO

West Orange Endocrinology has developed an excellent working relationship with different sponsors and CRO in the United States.

We conduct Phase II, III & IV studies to support requirements leading to new drug applications.

What We Offer

The Research Department at West Orange Endocrinology has earned a strong reputation with clinical research organizations and leading pharmaceutical companies. We consistently exceed recruitment and retention goals while maintaining high protocol compliance and data quality. Above all, the well-being and safety of our patients is our top priority.

Our team of experienced professionals and physicians is dedicated to conducting exceptional pharmaceutical research with a personalized, patient-focused approach. We provide comprehensive clinical pharmacology services across Phase II, III, and IV clinical trials, delivering reliable results that advance medical care and innovation.

Team Credentials

All staff is GCP certified
PI: Jose Mandry, >20 years of experience
Clinical Site Manager, >10 years of experience
CRC’s, 10-25 years of experience
On-site licensed ACLS
3 full-time patient recruitment staff members
1 Regulatory Specialists
Phlebotomist with IATA certification
1 licensed Dietician

WOE Facility Amenities

Secured, locked, limited access ambient drug room locked with limited access, refrigerator; limited access.
-20 degree freezer
Onsite lab with sample collection and shipping
Use central lab, ability to use Local clinical laboratory for safety and STAT results,
Dry ice available
Security system with alarm and cameras
Private room for consenting
1 room for monitor visits with Wi-Fi.
Dedicated exam room.
On-site storage for closed study files
On-site access to physicians
Local hospital only 0.4 miles away
Parking Lot

WOE Equipment

-20 freezer
Incubators
Ambient and refrigerated drug storage on site
Temperature monitoring
Ambient centrifuge
Accurate certified patient scales
12 lead ECG units
Pulse oximetry units
Scale to weigh study drug
Glucose monitoring system
Electronic Blood pressure equipment
Back-up generator
Back up Refrigerator
IV infusion pump
**All equipment is calibrated every 12 months or less.

Volunteer Recruitment

Our dedicated recruitment staff maintains an ever-expanding and detailed database continually updated and replenished through Dr. Mandry’s daily patients, referrals from advertisements, private practices, and recruitment websites, that allows us to access suitable volunteers based on important demographic input that encompasses all major groups for volunteer populations.

WOE Central Labs

Q2 Solutions (Quintiles)
PPD
MedPace
Quest
LabCorp

WOE Source

West Orange Endocrinology research department has developed valuable source documents, which are designed and tailored to follow the visit process ensuring all viable trial data is captured for the sponsor.
Also, all source documents are kept in a color code hard 3-ring binder which is labeled appropriately from informed consent to adverse events; this is to ensure consistency and accuracy.
A typical patient source binder would have the following labels: 1. Demographics 2. Informed consent 3. Medical history- which is signed by Principal Investigator and signed. 4. Concomitant Medications 5. Flow Sheet 6. Adverse event / SAE. 7. Visits according to protocol 8. Lab reports/ ECG’s